Which site in the ribosome is responsible for the recycling of tRNA?

The E site of the ribosome is specifically involved in the recycling of tRNA. During the process of translation, after a tRNA molecule has delivered its amino acid to the growing polypeptide chain and the ribosome shifts, the tRNA that was in the P site is moved to the E site. This is where the tRNA is released from the ribosome and can be reused in another round of translation. The E site serves as the exit site for tRNA, allowing it to disassociate from the ribosome once it has completed its function.

In contrast, the A site is where incoming aminoacyl-tRNA molecules enter the ribosome, and the P site is responsible for holding the tRNA with the growing polypeptide chain. The T site is not a formally recognized site in ribosome function. Understanding the specific roles of these sites provides insight into the efficient operation of the ribosome during protein synthesis.